Prevalence of Invasive Aspergillosis
Among (PTB) Patients
in Kanchipuram, India
Published: March 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.4094
Sivasankari S., Senthamarai S., Anitha C., Apurba Sankar Sastry, Sandhya bhatt, Kumudhavathi M.S., Amshavathani S.K.
1. Assistant Professor, Department of Microbiology, Meenakshi Medical College and Research Institute, Enathur, Kachipuram, Tamil Nadu, India.
2. Associate Professor, Department of Microbiology, Meenakshi Medical College and Research Institute, Enathur, Kachipuram, Tamil Nadu, India.
3. Assistant Professor, Department of Microbiology, Meenakshi Medical College and Research Institute, Enathur, Kachipuram, Tamil Nadu, India.
4. Assistant Professor, Department of Microbiology, JIPMER, Pondicherry, Tamil Nadu, India.
5. Assistant Professor, Department of Microbiology, PIMS, Pondicherry, Tamil Nadu, India.
6. Tutor, Department of Microbiology, Meenakshi Medical College and Research Institute, Enathur, Kachipuram, Tamil Nadu, India.
7. Professor & HOD, Department of Microbiology, Meenakshi Medical College and Research Institute, Enathur, Kachipuram, Tamil Nadu, India.
Correspondence
Dr. Sivasankari S.,
Assistant Professor, Department of Microbiology, Meenakshi Medical College and Research Institute,
Enathur, Kachipuram, Tamil Nadu, India.
Phone: (0)9444145904, E-mail: murugansivasankari1@gmail.com
Background: Tuberculosis (TB) remains a major health problem worldwide. (PTB) is commonly associated with secondary aspergilloma. Repeated exposure of Aspergillus spores can aggravate the bronchial pathology and can manifest as asthmatic episodes.
Aim and Objective: Pulmonary invasive aspergillosis is difficult to evaluate. Culture based diagnosis is time consuming. Hence (PCR) was done to evaluate the invasive fungal aspergillosis in (PTB) patients.
Materials and Methods: Eighty sputum samples collected from TB patients were processed as per standard protocol. Species level identification was done using PCR.
Results: Among 80 patients, 26 isolates were obtained, only 8 were Aspergillus species. All Aspergillus were taken up for PCR evaluation.
Conclusion: Fungal infection should be suspected in all sputum positive patients. PCR is an effective tool to diagnose invasive aspergillosis.
[
FULL TEXT ] | [ PDF]